Genome analysis reveals pili in Group B Streptococcus.
نویسندگان
چکیده
Pili are essential virulence factors in many Gram-negative bacteria; however, they have not been described in most important Gram-positive pathogens. While screening the sequence of multiple genomes of Group B Streptococcus, we identified protective antigens that formed high molecular weight polymers. Immunogold electron microscopy revealed that the structures have a pilus-like form. These large structures have gone unrecognized in decades of studies of Group B Streptococcus.
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ورودعنوان ژورنال:
- Science
دوره 309 5731 شماره
صفحات -
تاریخ انتشار 2005